Endocrine Abstracts

Propylthiouracil (PTU) treatment for thyrotoxicosis in pregnancy is common clinical practice. However maternal ingestion of PTU has been recognised to be associated with the development of foetal hypothyroidism and in rare cases at high doses of PTU, overt foetal goitre. Foetal goitre can be potentially dangerous due to mechanical obstruction and needs to be carefully monitored in utero. We report a case of development of goitre in utero secondary to maternal ingestion of PTU ...